Comparative in-vitro free radical scavenging activity of Murraya koenigii leaves extract and synthesized 1, 2, 3, 4-tetrahydrocarbazole and its derivatives

Authors

  • Meenakshi Mehra Paonta Sahib, Himachal Pradesh, India

DOI:

https://doi.org/10.21276/apjhs.2019.6.1.32

Keywords:

Murraya koenigii, DPPH, 1, 2, 3, 4-tetrahydrocarbazole, free radical scavenging activity

Abstract

The present study was designed to investigate the free radical scavenging activity of the chloroform extract of Murraya koenigii leaves and synthesized 1,2,3,4-tetrahydrocarbazole and its derivatives The chloroform extract was evaluated by TLC and its qualitative chemical investigation indicates the presence of alkaloid. Free radical scavenging activity of extract and synthesized compound was determined by DPPH free radical scavenging assay. Ascorbic acid taken as standard. Activity of extract and synthesized compounds were compared to reference compound, extract activity was lie between the activity of comp1and comp1a. Compound 1 and 1a was found to be most active among all synthesized compounds.

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Author Biography

Meenakshi Mehra, Paonta Sahib, Himachal Pradesh, India

Himachal Institute of Pharmacy, 

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Published

2019-03-30

How to Cite

Meenakshi Mehra. (2019). Comparative in-vitro free radical scavenging activity of Murraya koenigii leaves extract and synthesized 1, 2, 3, 4-tetrahydrocarbazole and its derivatives. Asian Pacific Journal of Health Sciences, 6(1), 237–242. https://doi.org/10.21276/apjhs.2019.6.1.32