A Study to Compare the Effect of Intrathecal 0.5% (Heavy) Bupivacaine With Dexmedetomidine (5µg) and Intrathecal 0.5% (Heavy) Bupivacaine With Fentanyl (25µg) For Lower Abdominal and Gynecological Surgeries

Abstract

Background: It is an established fact that regional anesthetic techniques especially through spinal route form an imperative for countries like India owing to their cheaper const, safety profile and ease of administration. Moreover, in lower abdominal and gynecological surgeries, they provide good muscle relaxation, higher success rate coupled with avoidance of multiple drugs. Aims and Objectives: The purpose of the study is to evaluate the efficacy of Dexmedetomidine (5µg) versus Fentanyl (25µg) as an adjuvant added to Bupivacaine in spinal anaesthesia and also to assess various hemodynamic parameters and side effects caused by them.Material and Methods: The current prospective study was conducted over a period of nineteen months from March 2017 to September 2018 at Government Medical College and Hospital, Anantapuramu and include a total of 50 cases were studied. Standard methods were used for recording as well as analysis of data.Observations and inference: It is observed in the study that that Intrathecal Dexmedetomidine produces early onset of sensory blockade significantly at 1.95±0.44 mins compared to Fentanyl at 2.89±0.42 mins and prolongs the duration of postoperative analgesia significantly up to 304.68 ±25.43 mins compared to Fentanyl where it is 253.12 ± 14.30 mins with desirable sedation and without significant side effects. Conclusion: It can be concluded from the study that intra the cal Dexmedetomidine is an ideal choice over Fentanyl for regional anesthesia