@article{Dr. Retina Paul_Nabamita Chaudhury_R. N. Misra_Shazad Mirza_Sankha Subhra Chaudhuri_Sukanta Sen_2018, title={Emerging importance of acinetobacter and its antibiogram in the recent era}, volume={5}, url={https://apjhs.com/index.php/apjhs/article/view/59}, DOI={10.21276/apjhs.2018.5.2.7}, abstractNote={<p>Background: Acinetobacter is widely distributed in nature as saprophytes. Recently, they have emerged as a nosocomial pathogen<br>due to its ability for survival in the hospital environment on a wide range of dry and moist surface. They cause pneumonia, urinary<br>tract infection (UTI), and surgical site infection (SSI) where drain tips are inserted, endocarditis, meningitis, peritonitis, and<br>bacteremia. Antibiotic susceptibility pattern of Acinetobacter may vary geographically. Due to multidrug resistance patterns of<br>Acinetobacter, it is imperative to know the institutional prevalent susceptibility profiles.<br>Aims and Objectives: This study was conducted to isolate Acinetobacter species from various clinical samples, to determine the<br>antibiotic susceptibility pattern and to carry out the epidemiological investigation of the isolates.<br>Materials and Methods: The study was conducted in a tertiary care hospital, over a period of 2 years. After identification, the<br>speciations of Acinetobacter isolates were done by biochemical tests and by VITEK 2. Antibiotic susceptibility was determined by<br>disc diffusion method. Extended-spectrum β-lactamases (ESBLs) and metallo-β-lactamases (MBLs) production were detected<br>by the combined disc diffusion test. An epidemiological study of Acinetobacter was carried out.<br>Results: Of 5096 infected samples, 505 (9.9%) were non-fermenting Gram-negative bacilli, among which 170 (33.8%) were<br>found to be Acinetobacter. The highest numbers of isolates were Acinetobacter baumannii, followed by Acinetobacter lwoffii,<br>Acinetobacter radioresistance, Acinetobacter calcoaceticus, Acinetobacter Haemolyticus, and Acinetobacter ursingii. Highest<br>incidences of susceptibility were to imipenem (60%), chloramphenicol, and gentamicin. ESBL and MBL productions were detected<br>in 23% and 17%, respectively.<br>Conclusion: A high level of antibiotic resistance was observed in this study and maximum isolation rate was in SSI. Most of<br>the patients had high-risk factors such as prolonged hospitalization, indwelling catheters, and orthopedics implants in situ or<br>other catheterization and diabetes. The analysis of susceptibility pattern will be useful in understanding the epidemiology of this<br>organism in our hospital setup.</p>}, number={2}, journal={Asian Pacific Journal of Health Sciences}, author={Dr. Retina Paul and Nabamita Chaudhury and R. N. Misra and Shazad Mirza and Sankha Subhra Chaudhuri and Sukanta Sen}, year={2018}, month={Jun.}, pages={25–32} }