TY - JOUR AU - Archana, AU - Vijay Singh, PY - 2022/06/25 Y2 - 2024/03/29 TI - Extraction, Purification, and Characterization of Lepidium sativum Mucilage for Product Development JF - Asian Pacific Journal of Health Sciences JA - APJHS VL - 9 IS - 4 SE - Articles DO - 10.21276/apjhs.2022.9.4S.29 UR - https://apjhs.com/index.php/apjhs/article/view/2755 SP - 81-86 AB - <p>Since ancient times, various human civilization are using herbal medications for different ailments. Herbal medications are being extensively researched and promoted in various health care programs in India. Scientist from across the globe is attracted toward the potential medicinal values of different herbs and is working to blend herbal medications with novel formulation technologies to overcome the difficulty associated in developing formulations based on herbal medications. Cress or garden cress (Lepidium sativum) has been widely reported for its numerous pharmacological activities. The cress seeds possess numbers of nutraceutical values from rubefacient, galactogogue, and laxative to diuretic properties. In the present study, mucilage is extracted from the seeds of L. sativum by different methods, in which the treatment of dried of mucilage powder with ethanol yields highest amount of mucilage. Further, purification was done exploiting the method of Munir et al. with slight modification. Chemical characterization shows presence of carbohydrate, mucilage, and polysaccharide. Proximate analysis also confirms the presence of crude fats (2.37%), proteins (3.07%), fibers (4.71%), and carbohydrates (77.72%) and total calculated energy was 287.62 kcal/gm. Physiochemical analysis shows 4.8% loss of moisture on drying; particle size of grinded mucilage 500–1000 μm; 7.6 pH of 0.5% solution of L. sativum mucilage; 227–229°C charring temperature; good swelling and flow properties; and compressibility index 0.26 and 26.0% compressibility. Fourier-transform infrared analysis of L. sativum mucilage shows presence of O-H, C-H and C=O functional group. The extraction and characterization of L. sativum mucilage could be further used for possible product development.</p> ER -