TY - JOUR AU - D Sridhar, AU - Kiranmai, AU - Ch Ratnakaumar, PY - 2015/12/31 Y2 - 2024/03/28 TI - A Study on Estimation of plasma Fibrinogen and plasma fibrin degradation product (FDP) in women with preeclamptic pregnancy JF - Asian Pacific Journal of Health Sciences JA - APJHS VL - 2 IS - 4(s) SE - Table of Contents DO - 10.21276/apjhs.2015.2.2s.11 UR - https://apjhs.com/index.php/apjhs/article/view/987 SP - 60-63 AB - <p>BACKGROUND: Preeclampsia is one of the commonest complications of pregnancy. It is associated with a state of hypercoagulability. The present study aimed to estimate the plasma fibrinogen and plasma FDP levels in preeclampsiaas compared to normal pregnancies. METHODS: This is a case-control hospital based study with normal pregnant women (n=36) and women with preeclampsia (n=64) in their third trimester were included in the study. Preeclamptic group was classified in to mild (n=42) and severe (n=22) preeclampsia. Plasma fibrinogen and FDP levels were analysed, and compared between the groups. RESULTS: Preeclampsia and normal pregnancy groups were comparable for age and body mass index but preeclampsia group had higher blood pressures and less period of gestation (p&lt;0.0001). The levels of plasma fibrinogen (654.5±131.74 vs. 491.52±81.7 mg/dL) and plasma FDP (10.96±2.32 vs. 5.54±0.8 µg/L) were higher in the preeclampsia group as compared to normal pregnancy (p&lt;0.0001). Elevations in fibrinogen and FDP levels were more marked for severe preeclampsia group than mild preeclampsia group.CONCLUSION: Preeclampsia is associated with high fibrinogen and FDP levels as compared to normal pregnancies. Severe preeclampsia patients have greater elevations as compared to mild preeclampsia patients.</p> ER -