Assessment of Premarital Haemoglobin Genotype Counselling in the Control of Haemoglobinopathies in Osogbo, Southwestern Nigeria

Authors

  • Dr. Igbeneghu C College of HealthSciences, Ladoke Akintola University of Technology,Ogbomoso, Nigeria
  • Okanlawon B.M College of HealthSciences, Ladoke Akintola University of Technology,Ogbomoso, Nigeria
  • Akinsehinwa T.N College of HealthSciences, Ladoke Akintola University of Technology,Ogbomoso, Nigeria
  • Olisekodiaka M.J Faculty of Medicine, Nnamdi Azikiwe University,Awka, Anambra State,Nigeria

DOI:

https://doi.org/10.21276/apjhs.2017.4.2.12

Keywords:

Haemoglobinopathies, Haemoglobin Genotype, Counselling, Couples

Abstract

Introduction: Premarital haemoglobin genotype counselling is gradually becoming popular for joining a man and a woman together as husband and wife in Southwestern Nigeria but there are still many couples who marry without the benefit of this exercise. Aim: To assess the importance of premarital haemoglobin genotype counselling in the control of haemoglobinopathies. Methods: A total of 220 individuals comprising 110 individuals (55 couples) who had premarital haemoglobin genotype counselling and 110 individuals (55 couples) who had no such counselling participated in this study. A sample of 1 ml of blood was drawn from each participant for determination of haemoglobin genotype by cellulose acetate electrophoresis technique. Results: Haemoglobin genotype incompatibility was significantly higher in the non-counselled group (10.9%) than in the counselled group (1.8%) (p = 0.01). Of the 7 couples who were incompatible, 85.7% was HbAS/AS and 14.3% was HbAS/AC. In the noncounselled group, there was 1 in 44 chance of having a child living with sickle cell anaemia and 1 in 220 chance of having a child with HbSC disorder while in the counselled group there was only 1 in 220 chance of having a child with sickle cell anaemia. A non-counselled parent had 6.61 times the risk of a counselled parent of being incompatible with their partner. This study shows that premarital haemoglobin counselling plays a vital role in the control of haemoglobinopathies. Therefore it should be embraced by all stakeholders to contain the menace and harrowing experience of haemoglobinopathies.
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Author Biographies

Dr. Igbeneghu C, College of HealthSciences, Ladoke Akintola University of Technology,Ogbomoso, Nigeria

Department of Biomedical Sciences

Okanlawon B.M, College of HealthSciences, Ladoke Akintola University of Technology,Ogbomoso, Nigeria

Department of Biomedical Sciences

Akinsehinwa T.N, College of HealthSciences, Ladoke Akintola University of Technology,Ogbomoso, Nigeria

Department of Biomedical Sciences

Olisekodiaka M.J, Faculty of Medicine, Nnamdi Azikiwe University,Awka, Anambra State,Nigeria

Department of Chemical Pathology

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Published

2017-06-30

How to Cite

Dr. Igbeneghu C, Okanlawon B.M, Akinsehinwa T.N, & Olisekodiaka M.J. (2017). Assessment of Premarital Haemoglobin Genotype Counselling in the Control of Haemoglobinopathies in Osogbo, Southwestern Nigeria. Asian Pacific Journal of Health Sciences, 4(2), 81–85. https://doi.org/10.21276/apjhs.2017.4.2.12