Hepatoprotective Study of Grewia Asiatica

Authors

  • C. L. Monica Department of Environmental Science, V.R. Siddhartha Engineering College (Autonomous), Vijayawada, Andhra Pradesh, India
  • Z. Vishnuvardhan Department of Environmental Science, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India

DOI:

https://doi.org/10.21276/apjhs.2021.8.3.30

Keywords:

Grewia asiatica, Hepatoprotective property, SGOT, Triglycerides

Abstract

Introduction: Plants have always been a very good source of drugs. Liver disorders are nearly one of the lethal ailments in the globe now a day. Hence, in the present study, we intend to evaluate the hepatoprotective study of Grewia asiatica. Materials and Methods: G. asiatica was collected from hills of Tirupati, dried, and powdered. Healthy male Wistar albino rats with paracetamol and CCl4-induced liver damage were studied on day 1 and 7 for the serum glutamate oxaloacetate transaminase (SGOT), serum alanine transaminase (SGPT), ALKP, and total protein levels after the extract was given at different concentrations. The results were compared histologically. Results: The hepatoprotective effect of the plant extract and combination also proved by measuring the liver related parameters such as SGOT, SGPT, ALKP, and total protein which were elevated in disease but significantly reduce in standard and plant extract treated groups. Conclusion: G. asiatica plant extracts were safe for treating the hepatic diseases and did not show any toxicities or drug-related interactions but future pharmacokinetic studies required to validate the given result.

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Published

2021-07-22

How to Cite

C. L. Monica, & Z. Vishnuvardhan. (2021). Hepatoprotective Study of Grewia Asiatica. Asian Pacific Journal of Health Sciences, 8(3), 173–177. https://doi.org/10.21276/apjhs.2021.8.3.30

Issue

Vol. 8 No. 3 (2021): Vol 8 | Issue 3 | July - September 2021

Section

Articles

License

Copyright (c) 2021 C. L. Monica, Z. Vishnuvardhan

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Asian Pacific Journal of Health Sciences applies the Creative Commons Attribution (CC-BY) license to published articles. Under this license, authors retain ownership of the copyright for their content, but they allow anyone to download, reuse, reprint, modify, distribute and/or copy the content as long as the original authors and source are cited. Appropriate attribution can be provided by simply citing the original article.