Evaluation of phytochemical profile and antioxidant status of laboratory mode Dasamoolarishtam health tonic and a marketed product

Abstract

The mankind has been using the medicinal herbs in all the aspects of their life since time immemorial. Ayurvedic formulations are as old as the Vedic age (1500 BCE–500 BCE), recently a surge in preference of Ayurvedic medicines for their health care properties. Dasamoolarishtam is an Ayurvedic preparation which contains both plant and non-plant ingredients. The aim of the current study is to prepare plant only Dasamoolarishtam through the extraction with ethanol solvent (DET). This preparation was evaluated for phytochemical constituents and antioxidant analysis and is compared with commercially available market sample/traditional formulation (MKT). The DET showed better results in all the studies such as qualitative and quantitative analysis of secondary metabolites as well as in vitro antioxidant parameters such as 2,2-diphenyl-1-picrylhydrazyl, 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid, ferric reducing antioxidant power, superoxide radical scavenging, and phosphomolybdenum assays. The results of the present study open up a new approach in the scientific preparation/modification of traditional medicines. The overall findings of the current research corroborate and validate the phytochemical and antioxidant properties of DET and MKT samples and also propose the scope for modification of Ayurvedic drug for more efficient and quick response during the treatment.