The Role of Probiotics in Alzheimer’s Disease

Authors

  • Siddharth S. Thakur School of Pharmaceutical sciences, Lovely Professional University, Phagwara, Punjab, India
  • Navneet Khurana School of Pharmaceutical sciences, Lovely Professional University, Phagwara, Punjab, India
  • Neha Sharma Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India, 3School of Pharmacy, Lingaya’s Vidyapeeth, Faridabad, Haryana, India
  • Neha Sharma School of Pharmaceutical sciences, Lovely Professional University, Phagwara, Punjab, India

DOI:

https://doi.org/10.21276/apjhs.2021.8.4S.8

Keywords:

Alzheimer’s disease, Amyloid precursor protein, Brain-derived neurotrophic factors, Central nervous system, Neurofibrillary tangles, Short-chain fatty acids.

Abstract

Alzheimer’s disease (AD) is a chronic and progressive neurodegenerative disease that starts slowly and gradually worsens over the time and further leads to cognitive impairment and causes dementia. Since it is the most common neurodegenerative disease in older adults, no successful treatment has been reported. However, many studies in AD are associated with gut microbial alterations. Probiotics are living microorganisms that provide health benefits when consumed in the proper amount. Some probiotic strains provide health benefits such as improving the intestinal environment, immunomodulatory functions, prevention of infections, anti-obesity effects, cancer-preventing effects, and extension of life span.
In contrast, some probiotic strains ameliorate cognitive impairment, CNS behavior, and depressive disorder. In many studies, probiotics have shown preventive and therapeutic potential in the case of AD. This review article aims to give a complete analysis of the role of probiotics in AD symptoms.

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Published

2021-12-31

How to Cite

Siddharth S. Thakur, Navneet Khurana, Neha Sharma, & Neha Sharma. (2021). The Role of Probiotics in Alzheimer’s Disease. Asian Pacific Journal of Health Sciences, 8(4), 45–48. https://doi.org/10.21276/apjhs.2021.8.4S.8

Issue

Vol. 8 No. 4 (2021): Vol 8 Issue 4 October-December(S) 2021

Section

Articles

License

Copyright (c) 2022 Siddharth S. Thakur, Navneet Khurana, Neha Sharma, Neha Sharma

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Asian Pacific Journal of Health Sciences applies the Creative Commons Attribution (CC-BY) license to published articles. Under this license, authors retain ownership of the copyright for their content, but they allow anyone to download, reuse, reprint, modify, distribute and/or copy the content as long as the original authors and source are cited. Appropriate attribution can be provided by simply citing the original article.