A Comparative Clinical Study of Kanchanar Guggulu and Varuna Shigru Guggulu along with Bala Taila Matra Basti in the Management of Mootraghata w.s.r. to Benign Prostatic Hyperplasia

Abstract

Background: Benign prostatic hyperplasia (BPH) is a benign enlargement of prostate gland commonly found in elderly men (50% found above 40 year of age) and responsible for major affecting factor for quality of life. The overall incidence rate of BPH is 15/1000 men per year. The present treatment modalities have their own complication and limitations. Hence, here is a need to approach a treatment aspect which can minimize the complication along with major relief effect. According to Ayurveda, considering Vata dosha (ApanaVata) as a main culprit for BPH/Mootraghata, line of treatment was planned to evaluate and compare the clinical efficacy of Kanchanar Guggulu and Varuna Shigru Guggulu, along with Matra basti of Bala Taila svata-kaphahar, mutrakrichahara, Lekhan, and shothahara along with oral medication. Materials and Methods: The patients having signs and symptoms of Mootraghata/BPH were registered and allocated into two groups by computer generated randomization method. Patients were treated with Kanchanar Guggulu orally (1 g thrice a day) in Group A (n = 40) and (1 g thrice a day) Group B (n = 41) for 21 days. Matra basti with 60 ml Bala Taila once a day was given in both groups for 21 days. Results: The result was drawn using appropriate statistical testes in objective as well subjective parameters and also to compare efficacy of both group treatment modalities. The trial drug depicted highly significant results in international prostate symptoms score (IPSS) symptoms, average urine flow rate and prostate size, and post-void residual urine (PVRU) in Group A, whereas Group B possessed highly significant effect on all the mentioned IPSS symptoms with improvement in the QOL, but significant changes were observed in PVRU. Conclusion: Final study concluded that Kanchanar Guggulu and Varuna Shigru Guggulu orally along with Bala Taila Matra bastiis safe and effective in the management of Mootraghata (BPH).