Prevalence and Antimicrobial Sensitivity Pattern of MRSA Isolated from Infection Wound, Catheters Swabs and Sewage Water Samples

Abstract

Nosocomial infection is a major problem in the world today. Methicillin- resistant Staphylococcus aureus (MRSA) strains, usually resistant to several antibiotics and also intrinsic resistance to ß- lactam antibiotics, shows a particular ability to spread in hospitals and now present in most of the countries. The present study was carried out to investigate the prevalence of MRSA and their rate of resistance to different anti staphylococcal antibiotics. A total of 100 health care associated (HA) sources such as wound, catheters swabs and sewage water samples were screened for MRSA and their antibiotic resistance pattern was performed. Out of 41 isolated strain of S.aureus, 34% were found to be methicillin resistant. There was high prevalence of MRSA in wound (44%), catheter samples (28%) and (22%) in sewage water sample. Almost all MRSA strains were resistant to penicillin followed by cloxacillin and cephalexin, co-trimoxazole. About 60-70% MRSA strains were resistant to erythromycin, ceftazidime, lincomycin, cephalexin, erythromycin and tetracycline. The determination of prevalence and antibiotic sensitivity pattern of MRSA will help the treating clinicians for first line treatment in referral hospitals.