Evaluation of interleukin-6 in non surgical periodontal therapy with & without laser: a clinico-biochemical study

Abstract

The aim of this clinical trial was to examine the clinical and biochemical efficacy of diode laser as an adjunct to scaling and root planing (SRP). 30 subjects were selected on basis of inclusion criteria and were categorized into two groups. After selection of subjects, 15 patients were included under control group and 15 patients were included under test group randomly. Plaque index, gingival index, bleeding on probing, probing depth, and clinical attachment level were measured at baseline, 1 month and 3 months after treatment. Interleukin-6 (IL-6), component of gingival crevicular fluid were analyzed by enzyme-linked immunosorbent assay. Better outcome was observed in test group compared to control group in full-mouth clinical parameters. The total amount of IL-6 value was decreased (p<0.05) after treatment in both the test as well as the control groups (p<0.05). The Diode laser provided significant improvements in clinical parameters which showed its positive effect on non surgical periodontal therapy