An Overview of Natural Disintegrating Agent Used in Dispersible Tablets

Abstract

The oral therapy is the most commonly used method for administering many medications since it is thought to be the safest, most practical, and least expensive method. Fast dissolving pills are highly popular right now because they dissolve or easily dissolve in the mouth after administration without the need for water. Fast dissolving tablets have been developed to address the drawbacks of conventional dose forms, particularly dysphagia (refers to problem in which it becomes difficult to swallow), in pediatric and geriatric patients. Natural materials offer an advantage in comparison to the synthetic ones since they are more easily accessible, cost effective, not harmful, and chemically inert. By acting as a binder, diluent, and superdisintegrant, natural polymers such as locust bean gum, banana powder, mango peel pectin, Mangifera indica gum, and Hibiscus rosa-sinensis mucilage improve tablet properties, increase the solubility of drugs which are insoluble or poorly soluble, helps in reducing the disintegration time, and aid as nutritional supplements. Natural polymer is derived from natural source, are economical, not harmful, decomposable, and environmentally helpful, free of negative effects, restorable, and serve as nutritional supplements. Studies have shown that natural polymers are more effective and safer than manufactured polymers. The aim of the current article is to study and examine natural polymers which have been approved by Food and Drug Administration for use in quick dissolving tablets.