Prevalence of High and Low -level Mupirocin, resistance against MRSA from a tertiary care hospital in eastern UP

Authors

  • Vidyut Prakash Banaras HinduUniversity, India
  • Deepak Kumar Banaras HinduUniversity, India
  • Sneha Samanta Banaras Hindu University, India
  • Jibananand Nayak Banaras Hindu University, India

DOI:

https://doi.org/10.21276/apjhs.2018.5.3.29

Keywords:

Mupirocin, MRSA, disk diffusion method

Abstract

Aim: To determine the prevalence of High and Low -level Mupirocin, resistance against MRSA from a tertiary care hospital in eastern UP was the aim of this study. Methods and Material: A total of 62 non duplicate previously confirmed MRSA isolates were included in this study. The Susceptibility testing andresult interpretation for determining the high and low level of mupirocin resistance was performed by disk diffusion method using 200 µg and 5 µg disc respectively as per Clinical and Laboratory Standards Institute (CLSI) M100-S25 recommendations. Results: A total of 60 isolates (96.8 %) were found sensitive to mupirocin, 2 isolates (3.2 %) had low-level mupirocin resistance whereas none of the isolates was found to have high-level mupirocin resistance. Conclusion: The high-level mupirocin-resistant is uncommon in our patient population. The Periodic monitoring is useful for detecting changing trends in mupirocin resistance as a risk of emergence of high level mupirocin resistant strains is there.

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Author Biographies

Vidyut Prakash, Banaras HinduUniversity, India

Department of Microbiology

Deepak Kumar, Banaras HinduUniversity, India

Department of Microbiology

Sneha Samanta, Banaras Hindu University, India

Department of Applied Microbiology

Jibananand Nayak, Banaras Hindu University, India

Department of Applied Microbiology

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Published

2018-09-30

How to Cite

Vidyut Prakash, Deepak Kumar, Sneha Samanta, & Jibananand Nayak. (2018). Prevalence of High and Low -level Mupirocin, resistance against MRSA from a tertiary care hospital in eastern UP. Asian Pacific Journal of Health Sciences, 5(3), 212–215. https://doi.org/10.21276/apjhs.2018.5.3.29

Issue

Vol. 5 No. 3 (2018): Vol 5 | Issue 3 | July - September 2018

Section

Table of Contents

License

Asian Pacific Journal of Health Sciences applies the Creative Commons Attribution (CC-BY) license to published articles. Under this license, authors retain ownership of the copyright for their content, but they allow anyone to download, reuse, reprint, modify, distribute and/or copy the content as long as the original authors and source are cited. Appropriate attribution can be provided by simply citing the original article.

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