A study of correlation of serum ferritin with glycated haemoglobin in diabetes mellitus type 2 patients: a case control study

Abstract

Context: Diabetes mellitus (DM) is one of the leading causes of morbidity and mortality worldwide and it has dreadful complications. It is important to disclose every hidden aspect of the diseases to control it in better way. Aim: To find association of elevated serum ferritin level with Diabetes mellitus (DM type 2) with and its correlation with level of glycated hemoglobin (HbA1c).Material and methods- The study population consisted of 108 individuals, out of them 53 were type 2 diabetic patients (case) and 55 were age and sex matched healthy individuals (control). Comparison of serum ferritin level was done between cases and controls. Correlation of serum ferritin level was seen with duration and severity of diabetes mellitus (DM type 2) and glycated haemoglobin (HbA1c).Results: Serum ferritin level of case group was found significantly higher than the control group and there was significant positive correlation of serum ferritin level with duration and poor control of DM type 2 and HbA1c. Conclusion: There can be a role of ferritin level as an indicator of control of glycaemia as HbA1c and Serum ferritin level can also be used as a marker of insulin resistance and duration of the disease.