Gastroretentive drug delivery system: an overview

Authors

  • Kauser Fatema Y.B. Chavan College of Pharmacy, Aurangabad, India
  • Tauqeer Shaikh Y.B. Chavan College of Pharmacy, Aurangabad, India
  • Zahid Zaheer Y.B. Chavan College of Pharmacy, Aurangabad, India
  • S.R.Shahi Government College of Pharmacy, Aurangabad, India

DOI:

https://doi.org/10.21276/apjhs.2016.3.4.22

Keywords:

Approaches of GRDDS, Evaluation parameters, Gastro-retentive drug delivery system, probablepolymers used in GRDDS, recent patents on GRDDS

Abstract

Gastric emptying is a complex process and makes the in vivo performance of the drug delivery system uncertain. In order to avoid this fickleness, efforts have been made to increase the retention time of the dosage form, that is the development to gastroretentive drug delivery system. Gastroretentive drug delivery system (GRDDS) can remain in the stomach for prolonged period of time and there by increases gastric residence time of drugs, and also improves the bioavailability of certain drugs. These are widely used for the site specific drug delivery, for the treatment of gastrointestinal diseases and disorders. There are several approaches of Gastroretentive drug delivery system which are discussed in detail in the present review. Recent patents on (GRDDS) are also enlisted with a detailed description of evaluation parameters of the same.

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Published

2016-12-30

How to Cite

Kauser Fatema, Tauqeer Shaikh, Zahid Zaheer, & S.R.Shahi. (2016). Gastroretentive drug delivery system: an overview. Asian Pacific Journal of Health Sciences, 3(4), 131–144. https://doi.org/10.21276/apjhs.2016.3.4.22

Issue

Vol. 3 No. 4 (2016): Vol 3 | Issue 4 | October - December 2016

Section

Table of Contents

License

Asian Pacific Journal of Health Sciences applies the Creative Commons Attribution (CC-BY) license to published articles. Under this license, authors retain ownership of the copyright for their content, but they allow anyone to download, reuse, reprint, modify, distribute and/or copy the content as long as the original authors and source are cited. Appropriate attribution can be provided by simply citing the original article.