Comparative study of magnesium sulphate regimens –pritchard regimen and dhaka regimen in the management of antepartum eclampsia

Abstract

Aims : To compare the effects of Magnesium sulphate regimens – Dhaka regimen with Pritchard regimen. The efficacy of controlling convulsions , In preventing recurrent convulsions, The incidence of complications Materials and Methods: The present study was conducted in 50 patients with antepartum eclampsia were recruited. Patients were divided into two groups of 25 each, Group A comprising of 25 patients who were given the Dhaka regimen, Group B comprising of 25 patients who were given the Pritchard regimen. Results: The mean age in
patients on Dhaka regimen was 21.6 years whereas the mean age in in patients on Pritchard regimen was 21.8 years. There was no significant difference observed in Premonitory symptoms between the two regimen groups p > 0.05. In the present study there was no significant difference in past history of eclampsia/ preeclampsia was observed between the two regimen groups In the present study it was observed that in both the groups majority of patients were admitted between 0 – 6 hrs Dhaka regimen (88%), pritchard (84%), there was no significant difference in mean convulsion to admission interval in either groups p >0.05. Maintainence dose of MgsO4 was given when patellar reflex was present, respiratory rate> 12/min, urine output the previous 1hr exceeding 30 ml .In the present study it was observed that the toxic levels of Magnesium reached earlier in Pritchard whereas in Dhaka it was not the same. Conclusion: The study clearly shows that Dhaka regimen is equivalent to Pritchard regimen in controlling convulsions and preventing recurrence of convulsions, with no difference.