Comparative in-vitro free radical scavenging activity of Murraya koenigii leaves extract and synthesized 1, 2, 3, 4-tetrahydrocarbazole and its derivatives
Keywords:Murraya koenigii, DPPH, 1, 2, 3, 4-tetrahydrocarbazole, free radical scavenging activity
The present study was designed to investigate the free radical scavenging activity of the chloroform extract of Murraya koenigii leaves and synthesized 1,2,3,4-tetrahydrocarbazole and its derivatives The chloroform extract was evaluated by TLC and its qualitative chemical investigation indicates the presence of alkaloid. Free radical scavenging activity of extract and synthesized compound was determined by DPPH free radical scavenging assay. Ascorbic acid taken as standard. Activity of extract and synthesized compounds were compared to reference compound, extract activity was lie between the activity of comp1and comp1a. Compound 1 and 1a was found to be most active among all synthesized compounds.
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