Lipid profile abnormalities in human immunodeficiency virus infected patients- a hospital based study

Abstract

The pandemic of Acquired Immunodeficiency Syndrome (AIDS) continues to take a tragic toll on the lives of people in South East Asia, Africa and rest of the world. The most common cardiovascular findings are nonspecific ST and T wave changes dyslipidemia and Human Immunodeficiency Virus (HIV) associated cardiomyopathy. This continues to be even more prevalent as an adverse effect of the HAART therapy. The rationale of the present study was to assess the prevalence of lipid profile abnormalities in a study population of Jharkhand (Eastern India) done in Rajendra Institute of Medical Sciences (RIMS), Ranchi, at the Department of Medicine. The analysis revealed that the total cholesterol was significantly lower for the cases compared to the control group. HDL and LDL cholesterol were significantly lower, whereas TC/HDL was significantly higher. 60% of our patients were having a CD 4 count less than 200. The lower the CD 4 count higher was the chance for the patient to have an abnormal lipid profile.