An Up-to-Date Review on Guillain–Barre Syndrome

Authors

  • Harpreet Singh Research Laboratory, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India.
  • Asheesh Kumar Gupta Research Laboratory, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India.
  • Arvind Kumar Research Laboratory, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India.
  • Amrita Mishra Research Laboratory, School of Pharmaceutical Sciences, IFTM University, Moradabad, Uttar Pradesh, India.
  • Abhishek Sharma Central Facility of Instrumentation, Pharmacy Academy, IFTM University, Moradabad, Uttar Pradesh, India.
  • Arun Kumar Mishra Central Facility of Instrumentation, Pharmacy Academy, IFTM University, Moradabad, Uttar Pradesh, India.
  • Vikas Kumar Chaudhari Department of Pharmacy, Rajkiran College of Pharmacy, Moradabad, Uttar Pradesh, India.

Keywords:

Acute paralytic polyneuropathy, Demyelination, Guillain–Barre Syndrome, Peripheral nerves

Abstract

Guillain–Barré syndrome (GBS) is an infrequent acute paralytic polyneuropathy that impacts around one in every 1 lakh people. It can affect both children and adults. GBS is an autoimmune condition of the peripheral nervous system that is developed due to an immune-mediated response to antigens that react with the myelin sheath of peripheral nerves, causing demyelination and/or axonal injury. In serious conditions, GBS can cause respiratory failure and even death also. The treatment with intravenous immunoglobulin and/or plasmapheresis, with an aim to neutralize and dispose the circulating antibodies from the bloodstream, respectively, in addition to supportive measures to maintain motor function of nervous system is presently available.

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Published

2022-06-25

How to Cite

Harpreet Singh, Asheesh Kumar Gupta, Arvind Kumar, Amrita Mishra, Abhishek Sharma, Arun Kumar Mishra, & Vikas Kumar Chaudhari. (2022). An Up-to-Date Review on Guillain–Barre Syndrome. Asian Pacific Journal of Health Sciences, 9(4), 233–237. Retrieved from https://apjhs.com/index.php/apjhs/article/view/2797