An Up-to-Date Review on Guillain–Barre Syndrome
Keywords:
Acute paralytic polyneuropathy, Demyelination, Guillain–Barre Syndrome, Peripheral nervesAbstract
Guillain–Barré syndrome (GBS) is an infrequent acute paralytic polyneuropathy that impacts around one in every 1 lakh people. It can affect both children and adults. GBS is an autoimmune condition of the peripheral nervous system that is developed due to an immune-mediated response to antigens that react with the myelin sheath of peripheral nerves, causing demyelination and/or axonal injury. In serious conditions, GBS can cause respiratory failure and even death also. The treatment with intravenous immunoglobulin and/or plasmapheresis, with an aim to neutralize and dispose the circulating antibodies from the bloodstream, respectively, in addition to supportive measures to maintain motor function of nervous system is presently available.
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Copyright (c) 2022 Harpreet Singh, Asheesh Kumar Gupta, Arvind Kumar, Amrita Mishra, Abhishek Sharma, Arun Kumar Mishra, Vikas Kumar Chaudhari
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