Estimation of Serum Lipid Profile Patterns As A Diagnostic Marker In Oral Cancer and Precancer

Authors

  • Dr. Kavitha Gaddikeri S.B Patil Dental College and Hospital,Bidar, Karnataka, India
  • Deepak D Bhorgonde S.B Patil Dental College and Hospital, Bidar, Karnataka,India

DOI:

https://doi.org/10.21276/apjhs.2016.3.4s.9

Keywords:

leukoplakia, lipid, oral cancer, triglycerides, total cholesterol

Abstract

Background: Lipids play a main role in maintenance of cell membrane integrity. Variation in serum lipid levels has been related with cancers. Aims and Objectives: To estimate serum lipid profile levels in oral cancer and precancer patients and to find out their role as a diagnostic and prognostic marker. Materials and Methods: Our study included 20 patients with oral cancer, 20 with precancerous lesions and 10 normal patients. In all these 50 subjects, serum lipid profile: Total cholesterol, Triglycerides (TGL), High density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL) and very low density lipoprotein cholesterol (VLDL) were analyzed using automatic analyzer. Results: When compared with controls, there was a significant decrease in levels of TC, TGL, HDL, LDL and VLDL in oral cancer and precancer patients. The mean serum lipid profiles were not statistically significant with respect to the oral cancer and precancer groups. Conclusion: There is a significant inverse relationship between serum lipid profile and oral cancer and precancer.

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Author Biographies

Dr. Kavitha Gaddikeri, S.B Patil Dental College and Hospital,Bidar, Karnataka, India

Reader, Department of Oral & Maxillofacial
Pathology

Deepak D Bhorgonde, S.B Patil Dental College and Hospital, Bidar, Karnataka,India

Professor & Head, Department of Prosthodontics

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Published

2016-12-31

How to Cite

Dr. Kavitha Gaddikeri, & Deepak D Bhorgonde. (2016). Estimation of Serum Lipid Profile Patterns As A Diagnostic Marker In Oral Cancer and Precancer. Asian Pacific Journal of Health Sciences, 3(4(S), 59–62. https://doi.org/10.21276/apjhs.2016.3.4s.9

Issue

Vol. 3 No. 4(S) (2016): Vol 3 | Issue 4(S), October - December 2016

Section

Table of Contents

License

Asian Pacific Journal of Health Sciences applies the Creative Commons Attribution (CC-BY) license to published articles. Under this license, authors retain ownership of the copyright for their content, but they allow anyone to download, reuse, reprint, modify, distribute and/or copy the content as long as the original authors and source are cited. Appropriate attribution can be provided by simply citing the original article.