Assessment of role of mast cells in oral squamous cell carcinoma

Authors

  • Dr. Kavitha Gaddikeri S.B Patil Dental College and Hospital, Bidar,Karnataka, India

DOI:

https://doi.org/10.21276/apjhs.2016.3.4s.10

Keywords:

Mast cells, Oral squamous cell carcinoma, Toluidine blue stain

Abstract

Background: Mat cells play a crucial role in homeostasis and inflammation. Recently mast cells have been associated with numerous malignancies like oral squamous cell carcinoma (OSCC).Aims and Objectives: To compare mast cell density in normal mucosa and squamous cell carcinoma and to assess the role of mast cells in oral squamous cell carcinoma.Materials and Methods: Our retrospective study included 40 specimens, 10 well differentiated OSCC, 10 moderately differentiated OSCC, 10 poorly differentiated OSCC and 10 controls. Mast cell density was determined by toluidine blue staining. Statistical analysis was carried out using Statistical Package for Social Sciences (SPSS) 17.0 version (SPSS Inc., Chicago, IL, USA).Results: When compared with controls, mast cells count was a higher in OSCC groups which was a statistically significant (P < 0.001). Conclusion: Mast cells have a significant role in OSCC.

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Author Biography

Dr. Kavitha Gaddikeri, S.B Patil Dental College and Hospital, Bidar,Karnataka, India

Reader,Department of Oral & Maxillofacial Pathology

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Published

2016-12-31

How to Cite

Dr. Kavitha Gaddikeri. (2016). Assessment of role of mast cells in oral squamous cell carcinoma. Asian Pacific Journal of Health Sciences, 3(4(S), 63–66. https://doi.org/10.21276/apjhs.2016.3.4s.10

Issue

Vol. 3 No. 4(S) (2016): Vol 3 | Issue 4(S), October - December 2016

Section

Table of Contents

License

Asian Pacific Journal of Health Sciences applies the Creative Commons Attribution (CC-BY) license to published articles. Under this license, authors retain ownership of the copyright for their content, but they allow anyone to download, reuse, reprint, modify, distribute and/or copy the content as long as the original authors and source are cited. Appropriate attribution can be provided by simply citing the original article.