Anticancer Potential of Triazine Scaffold: A Brief Review

Authors

  • Meenakshi Saini Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India
  • Saloni Kakkar Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India
  • Ashu Sapra Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India
  • Priyanka Suhag Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India

DOI:

https://doi.org/10.21276/apjhs.2022.9.1.50

Keywords:

Anticancer, Antimicrobial, Heterocyclic compounds, Rational medicine, Triazine derivatives

Abstract

Triazine is an important class of heterocyclic compounds. Triazine is a six-membered heterocyclic compound with three carbons replaced by nitrogen in the benzene ring. Triazine and its compounds exhibit a wide variety of pharmacological activity such as antifungal, anti-HIV, anticancer, antioxidant, anti-inflammatory, analgesic, antihypertensive, antiviral, antimalarial, antiprotozoal, and antibacterial. The triazine ring has been modified at different positions to generate new molecules. The structure of the new derivatives was characterized by common analytical method. Some examples of triazine compounds commonly used in rational medicine are: Ceftriaxone as an antimicrobial agent and 6-Azacytosine as an antiviral agent. The present review article enumerates on the biological potential of triazine and how it is beneficial to discover more new compounds that could be better in terms of efficacy and lesser toxicity.

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Published

2022-01-15

How to Cite

Meenakshi Saini, Saloni Kakkar, Ashu Sapra, & Priyanka Suhag. (2022). Anticancer Potential of Triazine Scaffold: A Brief Review. Asian Pacific Journal of Health Sciences, 9(1), 233–236. https://doi.org/10.21276/apjhs.2022.9.1.50