Anticancer Potential of Triazine Scaffold: A Brief Review
Keywords:Anticancer, Antimicrobial, Heterocyclic compounds, Rational medicine, Triazine derivatives
Triazine is an important class of heterocyclic compounds. Triazine is a six-membered heterocyclic compound with three carbons replaced by nitrogen in the benzene ring. Triazine and its compounds exhibit a wide variety of pharmacological activity such as antifungal, anti-HIV, anticancer, antioxidant, anti-inflammatory, analgesic, antihypertensive, antiviral, antimalarial, antiprotozoal, and antibacterial. The triazine ring has been modified at different positions to generate new molecules. The structure of the new derivatives was characterized by common analytical method. Some examples of triazine compounds commonly used in rational medicine are: Ceftriaxone as an antimicrobial agent and 6-Azacytosine as an antiviral agent. The present review article enumerates on the biological potential of triazine and how it is beneficial to discover more new compounds that could be better in terms of efficacy and lesser toxicity.
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Copyright (c) 2021 Meenakshi Saini, Saloni Kakkar, Ashu Sapra, Priyanka Suhag
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