PSORIASIS - A Mini Review

Abstract

Psoriasis is a chronic inflammatory squamous cell disease of papules that is characterized by multiple remissions and relapses. This has long been considered a serious violation of keratinization. The successful use of traditional immune suppressants and new immune modulators in the treatment of psoriasis has led to the belief that psoriasis is, in fact, a disorder of Th1 cell immunodeficiency. Recent developments have led to several new discoveries such as the role of Th17 cells and evidence of skin barrier dysfunction in psoriasis similar to atopic dermatitis. Psoriasis is an atypical, systemic autoimmune disease of unknown cause, mainly affecting the skin, spreading further to the nails and joints and causing arthritis. The treatment protocol should be based on the patient’s condition. People with mild psoriasis can be treated primarily with topical medications, while people with moderate to severe psoriasis can be treated with systemic medications.